Christine Carbone
Structural Biology Scientist Relay Therapeutics
Christine Carbone, PhD is currently a Scientist II in Structural Biology at Relay Therapeutics, having progressed from Scientist I in the same department since January 2023. Previously, Christine served as a PhD candidate at UMass Chan Medical School where significant research contributions included determining structures of the 70S ribosome•tRNA•mRNA•ArfB complex and capturing multiple states of EF-G•GTP catalyzed translocation via cryo-EM. Earlier roles included Lab Manager and Laboratory Technician at Worcester Polytechnic Institute, where responsibilities encompassed managing lab resources, conducting experiments on porcine circovirus, and training students.
Seminars
- Comparing access, cost, and timelines for large pharma versus biotechs, and when outsourcing or academic partnerships make more sense
- Addressing challenges around data volume, selection, and cloud storage
- How data processing, classification, and refinement workflows impact turnaround time and confidence in results
- Current constraints including size limits, flexibility, heterogeneity, and challenges with smaller molecules or weak interactions
- Emerging hardware, sample preparation strategies, and computational advances aimed at improving resolution, throughput, and applicability