Harnessing Artificial Intelligence & Cryo-EM to Accelerate Structure-Based Drug Discovery

• Leveraging machine learning–guided construct optimization to improve protein expression, stability, and cryo-EM suitability
• Accelerating structural determination of dynamic and difficult targets such as membrane proteins and large complexes
• Combining AI-assisted protein engineering with cryo-EM structural analysis to generate actionable SBDD insights

Speakers:

Huixian Wu

Director, Head of Structural Biology

Pfizer