Diving into Challenges, Applications & Innovations to Maximize Cryo-EM in Structure-Based Drug Design
Time: 8:30 am
day: Day 1
Details:
- Explore advancements in detector technology and data processing that are making cryo-EM suitable for smaller molecular weight targets and achieving higher resolution structures in drug discovery
- Delve into the latest approaches to optimize sample preparation, including grid freezing techniques, cryoprotectants, and methods to ensure uniform particle distribution for consistent results
- Examine how cryo-EM integrates with complementary techniques like X-ray crystallography and NMR, providing a multidimensional perspective in complex drug discovery workflows
