Overcoming the Flexible Nature of mRNA: Structure-Based Approaches to Predicting & Targeting Flexible Proteins
Time: 9:30 am
day: Day 2
Details:
- Address the challenge of predicting and designing drugs for flexible proteins, particularly those involved in mRNA translation
- Explore advanced structure-based methods, including molecular dynamics simulations, to capture protein flexibility and improve prediction accuracy
- A real-world case study demonstrating how overcoming flexibility-related challenges has led to successful therapeutic development