Leveraging Structural Insights for Protein Engineering & Drug Stability Optimization
Time: 1:00 pm
day: Day 1
Details:
- Examining how structural biology techniques, including crystallography and HDX, reveal conformational flexibility and drive protein engineering decisions
- Bridging structural insights with computational modelling to stabilize biologics and improve their pharmacokinetics in circulation
- Applying protein engineering strategies to mimic small-molecule-induced stabilization, enhancing therapeutic potential beyond traditional medicinal chemistry approaches
