Structural Advances in GPCR dynamics: Unlocking Drug Discovery through Cryo-EM
Time: 2:30 pm
day: Day 2
Details:
- Structural characterization of GPCRs in various conformational states is essential for understanding activation mechanisms, downstream pharmacology, and the development of biologic drugs.
- Advances in cryo-EM and innovative techniques have revolutionized membrane protein structural studies, overcoming challenges in GPCR-targeted drug discovery
- The Tectonic GEODe™ platform enables the stabilization of active and inactive GPCR conformations, enhancing the discovery of biologics and expanding therapeutic possibilities
