Structural Design Strategies for Developing Next-Generation Vaccines
Time: 11:30 am
day: Day 2
Details:
- Learn how structural biology enables the identification and design of stable, immunogenic epitopes, using technologies like cryo-EM and X-ray crystallography to tailor antigens that can trigger robust immune responses
- Discover how vaccine candidates are designed by optimizing antigen structures, addressing challenges like antigenic variation, and focusing on conserved regions to enhance broad protection against evolving pathogens
- Explore how structural insights are leading to the design of vaccines against “undruggable” or challenging targets, where understanding protein folding and conformational flexibility is key to developing novel immunogens
