Alexey Rak

Company: Sanofi

Job title: Head of Bio Structure and Biophysics

 

Seminars:

Advancing Structure-Based Drug Design: Tackling Challenging Targets and Complex Biologics 9:30 am

  • Leveraging structural biology techniques such as cryo-EM and hydrogen-deuterium exchange mass spectrometry to map antibody-drug conjugate (ADC) interactions with complex tumor-associated antigens
  • Addressing the structural constraints and conformational dynamics that impact binding specificity, with insights into distinguishing closely related protein families such as CEACAMs
  • Exploring how deep structural characterization informs the design of next-generation ADCs and other therapeutic modalities for precision targeting of difficult-to-drug proteins

day: Day 1

Panel & Audience Discussion: Beyond the AI Hype – Overcoming the Barriers to Fully Maximizing AI in Drug Design 5:00 pm

This panel brings together experts to discuss the real challenges in adopting AI in drug design, moving beyond the hype to practical solutions for overcoming barriers related to data quality, integration, and model reliability.

  • What are the current limitations and challenges in leveraging AI within the context of drug design and structural biology?
  • How can the scientific community ensure that AI models are properly validated, integrated with experimental data, and implemented in real-world workflows?
  • What advancements are needed in AI, data management, and experimental techniques to unlock its full potential for drug development?

day: Day 1

Alexey Rak