Douglas Kitchen

Company: CURIA

Job title: Research Fellow, Computer-Aided Drug Discovery, Discovery Services

 

Seminars:

Integrated Structure-Guided Drug Discovery accelerates success in early discovery research: A worked example from a challenging DNA-repair target, Artemis 9:15 am

  • Designing a new protein construct that provided the first crystal structure of Artemis
  • Discussing a unique screening library produced novel hits to an allosteric binding site
  • Highlighting efficient SAR development was enabled by more than 80 co-crystal structures and collaborative efforts of medicinal and computational chemistry
  • Understanding without these structures key induced-fit effects could not have been predicted

day: Day 2

Curia