Lionel Rougé

Company: Denali Therapeutics Inc.

Job title: Associate Director, Protein Sciences

 

Seminars:

Leveraging Structural Insights for Protein Engineering & Drug Stability Optimization 1:00 pm

  • Examining how structural biology techniques, including crystallography and HDX, reveal conformational flexibility and drive protein engineering decisions
  • Bridging structural insights with computational modelling to stabilize biologics and improve their pharmacokinetics in circulation
  • Applying protein engineering strategies to mimic small-molecule-induced stabilization, enhancing therapeutic potential beyond traditional medicinal chemistry approaches

day: Day 1

Lionel Rougé